Yan Zhihong Shanghai Yuanyue Light Industry Machinery Co., Ltd. always designs and selects Chinese medicine complete sets of equipment. The first thing to emphasize is the process, whether the new extraction process can be used to strengthen the extraction and concentration process, and the new process for the extraction of drugs and different components. Influence, on the basis of in-depth pharmacological research, looking for good operating conditions and possible mechanism of action, and then designing small industrial equipment. In terms of details, because it is a complete set of equipment, it is necessary to consider the working time and cycle of each equipment, and reasonably select the size of the equipment. During the same period, there may be no work interruption due to the size of the equipment. In addition, it is also necessary to pay attention to the problem of energy conservation. For complete sets of equipment, it is necessary to optimize the process as much as possible, shorten the corresponding pipelines, and reduce the energy consumption loss during the material transportation process. Reasonably arrange the installation location of the equipment to save space and save equipment costs. At the same time, it is also necessary to pay attention to its operability and the operator's operation is convenient, time-saving and labor-saving, making it more human. In other words, it is necessary to pay attention to the cost performance of the equipment in the early stage and the operation cost in the later stage, as well as the versatility and practicality of the equipment.
The choice of equipment is also related to the location of the enterprise. Just like the construction of a large city in a large city, the general level of a single floor is similar to the price/performance ratio. For example, the problem of condensed water commonly found in extraction and concentration, if it is not in a water-deficient area, to do cooling towers, cold water, pipelines, etc., but also pumping, the economic benefits may not be so obvious, many companies are not willing to do. So choose the right one, it is zui reasonable, zui economy.
Solemn Zhengzhou Tongsheng Pharmaceutical Co., Ltd. (1) select the main varieties of production; (2) similar or similar processes; (3) have a certain forward-looking production forecast; (4) rationally balance the material balance of each production unit to avoid There is a “card neck†unit; (5) the equipment layout minimizes the material transfer distance of the intermediate link; (6) when the main output variety changes, the replacement of the equipment, the reserved position; (7) the convenience and safety of operation.
Xiao Jieming Director of Hangzhou Chunjiang Institute of Automation (1) Design and selection of Chinese medicine complete sets of equipment should first comply with the provisions of GMP and its appendices. The process layout should follow the principle of coarse and fine first, and the production capacity of each unit equipment should be basically the same; (2) The purchase of traditional Chinese medicine complete sets of equipment should give priority to enterprises and products that implement and meet the national standards of pharmaceutical equipment to ensure purchase. The product quality of the equipment; (3) The relationship between function and output should be considered. When the output is small, multi-function net equipment should be selected to process various medicinal materials in a multi-purpose manner and reduce equipment investment. When the output is large, the equipment should be selected according to the shape and texture of the medicinal materials, and the process requirements should be met. (4) When searching for relevant materials, it is necessary to conduct on-the-spot investigations to understand the production scale, production capacity, processing equipment capacity, and technology development of equipment manufacturing enterprises. Capabilities and service capabilities, etc., for pressure vessels and other products, should also check the corresponding qualification certificate; (5) select the equipment produced by the same manufacturer as much as possible.
Zhao Kaijun Nanjing Zhongshan Pharmaceutical Co., Ltd. engineers must select the complete sets of Chinese medicine equipment to consider the supporting situation of each section. Taking the extraction and concentration equipment as an example, the extraction capacity should be compatible with the concentration ability, because the extracted liquid should enter the concentration process, and if the concentration efficiency cannot keep up, the next production will be affected. If the concentration ability is large and the extraction ability is small, the equipment is wasted. The equipment should be selected according to the actual situation of each pharmaceutical factory, because the various parameters of the equipment and the theoretical production efficiency vary according to the variety. Do not design the complete set of Chinese medicine equipment according to the theoretical production efficiency, must be based on its own variety. The actual choice is made.
The preparation process of Lin Yanhai Yunnan Bio-Valley Huanhua Pharmaceutical Co., Ltd. is an important part of preparation research. The research of preparation technology should be guided by the theory of traditional Chinese medicine. The prescription of the drug in the other agent should be analyzed, and the design of the route should be applied by modern science and technology. The research of process technology conditions screening and pilot test series, and the research data are sorted and summarized, so that the preparation process is scientific, reasonable, advanced and feasible, so that the developed preparations are safe, effective, controllable and stable.
Design and selection of Chinese medicine complete sets of equipment should pay attention to: (1) equipment capacity. Whether the production capacity of the equipment is consistent with the design capacity of the enterprise, whether the production capacity of each equipment of the entire extraction line is coordinated; (2) Material. Contact with any substance, whether the contact will react or corrode, whether there is any quality hazard in long-term use; (3) The process requires the detection means in production, whether the production equipment can do it. (4) Cleaning of equipment. Whether the equipment is clean, those places are dead corners when cleaning; (5) Whether the equipment is well maintained, when the fault occurs, whether the repair of the manufacturer is convenient and timely; (6) The safety of the equipment design. Whether the production process, maintenance process is designed with safety switch, whether the existing equipment has unsafe factors; (7) the energy used by the equipment; (8) whether the appearance (height, volume) of the equipment is suitable for the existing plant.
Wei Zengyu Lianyungang Chinese Medicine Higher Vocational and Technical School Pharmaceutical Preparation Training Center Engineer (1) The material of the equipment must meet the requirements of the new GMP clause of zui; (2) The selection of complete sets of equipment should be based on the production process with pilot scale amplification. Otherwise, according to the equipment modification process, it will bring potential risks to the production of drugs; (3) The design and selection of equipment should consider the requirements of sanitation and cleaning. The pretreatment equipment of traditional Chinese medicine has higher requirements on the environment, because the traditional Chinese medicine pretreatment process is rich in variety. The workload is large, the dust is much, the water is used, the air is humid, and it is easy to cause quality accidents such as confusion and pollution. For how to quickly clean the equipment and reduce the workload of the personnel, it is necessary to consider in the selection stage; (4) Refinement of traditional Chinese medicine The process is constantly improving, so some interfaces should be reserved during the design and selection of the equipment to facilitate the process improvement.
The choice of equipment is also related to the location of the enterprise. Just like the construction of a large city in a large city, the general level of a single floor is similar to the price/performance ratio. For example, the problem of condensed water commonly found in extraction and concentration, if it is not in a water-deficient area, to do cooling towers, cold water, pipelines, etc., but also pumping, the economic benefits may not be so obvious, many companies are not willing to do. So choose the right one, it is zui reasonable, zui economy.
Solemn Zhengzhou Tongsheng Pharmaceutical Co., Ltd. (1) select the main varieties of production; (2) similar or similar processes; (3) have a certain forward-looking production forecast; (4) rationally balance the material balance of each production unit to avoid There is a “card neck†unit; (5) the equipment layout minimizes the material transfer distance of the intermediate link; (6) when the main output variety changes, the replacement of the equipment, the reserved position; (7) the convenience and safety of operation.
Xiao Jieming Director of Hangzhou Chunjiang Institute of Automation (1) Design and selection of Chinese medicine complete sets of equipment should first comply with the provisions of GMP and its appendices. The process layout should follow the principle of coarse and fine first, and the production capacity of each unit equipment should be basically the same; (2) The purchase of traditional Chinese medicine complete sets of equipment should give priority to enterprises and products that implement and meet the national standards of pharmaceutical equipment to ensure purchase. The product quality of the equipment; (3) The relationship between function and output should be considered. When the output is small, multi-function net equipment should be selected to process various medicinal materials in a multi-purpose manner and reduce equipment investment. When the output is large, the equipment should be selected according to the shape and texture of the medicinal materials, and the process requirements should be met. (4) When searching for relevant materials, it is necessary to conduct on-the-spot investigations to understand the production scale, production capacity, processing equipment capacity, and technology development of equipment manufacturing enterprises. Capabilities and service capabilities, etc., for pressure vessels and other products, should also check the corresponding qualification certificate; (5) select the equipment produced by the same manufacturer as much as possible.
Zhao Kaijun Nanjing Zhongshan Pharmaceutical Co., Ltd. engineers must select the complete sets of Chinese medicine equipment to consider the supporting situation of each section. Taking the extraction and concentration equipment as an example, the extraction capacity should be compatible with the concentration ability, because the extracted liquid should enter the concentration process, and if the concentration efficiency cannot keep up, the next production will be affected. If the concentration ability is large and the extraction ability is small, the equipment is wasted. The equipment should be selected according to the actual situation of each pharmaceutical factory, because the various parameters of the equipment and the theoretical production efficiency vary according to the variety. Do not design the complete set of Chinese medicine equipment according to the theoretical production efficiency, must be based on its own variety. The actual choice is made.
The preparation process of Lin Yanhai Yunnan Bio-Valley Huanhua Pharmaceutical Co., Ltd. is an important part of preparation research. The research of preparation technology should be guided by the theory of traditional Chinese medicine. The prescription of the drug in the other agent should be analyzed, and the design of the route should be applied by modern science and technology. The research of process technology conditions screening and pilot test series, and the research data are sorted and summarized, so that the preparation process is scientific, reasonable, advanced and feasible, so that the developed preparations are safe, effective, controllable and stable.
Design and selection of Chinese medicine complete sets of equipment should pay attention to: (1) equipment capacity. Whether the production capacity of the equipment is consistent with the design capacity of the enterprise, whether the production capacity of each equipment of the entire extraction line is coordinated; (2) Material. Contact with any substance, whether the contact will react or corrode, whether there is any quality hazard in long-term use; (3) The process requires the detection means in production, whether the production equipment can do it. (4) Cleaning of equipment. Whether the equipment is clean, those places are dead corners when cleaning; (5) Whether the equipment is well maintained, when the fault occurs, whether the repair of the manufacturer is convenient and timely; (6) The safety of the equipment design. Whether the production process, maintenance process is designed with safety switch, whether the existing equipment has unsafe factors; (7) the energy used by the equipment; (8) whether the appearance (height, volume) of the equipment is suitable for the existing plant.
Wei Zengyu Lianyungang Chinese Medicine Higher Vocational and Technical School Pharmaceutical Preparation Training Center Engineer (1) The material of the equipment must meet the requirements of the new GMP clause of zui; (2) The selection of complete sets of equipment should be based on the production process with pilot scale amplification. Otherwise, according to the equipment modification process, it will bring potential risks to the production of drugs; (3) The design and selection of equipment should consider the requirements of sanitation and cleaning. The pretreatment equipment of traditional Chinese medicine has higher requirements on the environment, because the traditional Chinese medicine pretreatment process is rich in variety. The workload is large, the dust is much, the water is used, the air is humid, and it is easy to cause quality accidents such as confusion and pollution. For how to quickly clean the equipment and reduce the workload of the personnel, it is necessary to consider in the selection stage; (4) Refinement of traditional Chinese medicine The process is constantly improving, so some interfaces should be reserved during the design and selection of the equipment to facilitate the process improvement.
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