Release date: 2016-12-12
Nuclear medicine is a medical discipline that applies radioactive substances to the body and is a key part in diagnosing and determining the severity of a patient's disease. However, it is foreseeable that the use of radioactive equipment also poses certain risks. Radiation is harmful to the body, so the key to nuclear medicine is to control and reduce the amount of radioactive material added to the body, either orally or intravenously. This is what 3D printing is all about: a team of researchers from the University of Würzburg in Germany showed how 3D printed organ models play an important role in the dose testing of radioactive materials for clinical prototyping.
For those unfamiliar with nuclear medicine research, the research process mainly involves injecting a small amount of radioactive substances into the body, and then capturing the mark by an external detector to give the doctor a clear indication of which abnormalities or diseases such as cancer, heart disease, The manifestations of neurological diseases and the like in the body. The new 3D printing research, published in the December issue of the Journal of Nuclear Medicine, outlines how a low-cost 3D printed organ model can better understand how much radioactive material should be injected into a particular patient. One of the study authors, Dr. Johannes Tran-Gia, said: "This study provides a low-cost patient-specific organ/lesion model for direct and patient-specific calibration, which is low for spatial resolution. Definitive quantitative imaging systems such as SPECT / CT are particularly important." (SPECT stands for Single Photon Emission Computed Tomography)
As part of the research, researchers 3D printed a set of kidney models to show how their technology can benefit medical professionals. The kidneys were chosen as test organs because of their sensitivity to radionuclide therapy. As you can see in the photo, each size of the 3D printed kidney reflects the volume of different ages. The smallest, 8mL, represents a newborn's kidney, the largest, 123mL, which is the average adult size. The researchers said the size is based on the size of the kidney provided by the Medical Internal Radiation Dose (MIRD) guidelines.
The phantom kidney model printed on the FDM 3D printer is made of a waterproof and chemically stable plastic material. It is worth mentioning that 3D printed phantom kidneys are refillable, so researchers have been able to test the addition of different doses of radioactive materials to determine the amount of radioisotope required for SPECT or CT scans. As described in the study, "nuclear-dependent SPECT/CT calibration factors é”-99m (Tc-99m), é•¥-177 (Lu-177) and iodine-131 (I-131) were determined to assess accurate internal renal dosimetry Sexual quantitative imaging... Although in our study, the kidney was modeled as a relatively simple single-compartment model, the study represents an important step in the reliable determination of absorbed dose, followed by dosimetry in individualized patients. Other key organs of the kidney."
Research conducted by the University of Würzburg team demonstrates how 3D printing can be used in nuclear medicine and how low-cost 3D printing models can facilitate clinical prototyping.
(Compiled from 3Ders.org)
Source: Tiangongshe
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