Diagnose gum disease and do this "squid ink"

Release date: 2017-09-12

One tooth test is particularly painful, and that is the detection of periodontal disease. A sharp probe looking for signs of disease on the gums is not only time-consuming, but sometimes causes bleeding, making the patient very scared, and the doctors are not good enough. They wonder if they will not see the important symptoms.

Such unfriendly testing methods may also miss the symptoms, which is really need to be improved. Now, Professor Jesse Jokerst, a nanoengineer from the University of California, San Diego, says he has a solution for imaging the gums by sputuming them with squid ink.

This way sounds a lot simpler, but squid ink? Yes, you think there is nothing wrong with it. It is a squid. It has a close relationship with squid and is often used to make food. For example, squid ink can be used to make squid ink pasta, so this ink is very safe, it will not stain the teeth, just a simple brush can be removed.

How does squid ink help the disease detection of the gums? Laser and ultrasound help are also needed.

In an article recently published in the Journal of Dental Research, Jokerst and his colleagues describe this approach. The researchers used high-resolution photoacoustic ultrasound to measure the depth of the sulcus. Ultrasound is used after the ink (very dark liquid, filled with melanin nanoparticles, absorbing a lot of light). Jokerst says that when bombarded with a laser, the ink in the mouth heats up and swells, creating a pressure differential in the gingival sulcus, which can be easily detected by ultrasound. This is a non-invasive method and is time-saving and accurate than the probe.

I wanted to study such a non-invasive test method because Jokerst had an unpleasant experience when I was at the dentist. When the dentist used the probe to check at his gums, the scratches and tingles caused him I think this is really not a good idea.

“These tools are too outdated,” he said. “Have you seen the periodontal probe? It’s just a metal rod.”

For decades, the gold standard for measuring periodontal disease has been to use these hook-shaped sticks to measure the "ditch depth" - the gap between the gums and the teeth, and the diseased person's sulcus is deeper than healthy people. But the process of detection is cumbersome and painful. This process is not liked by patients, and dentists don't like it.

Dr. Arezou Goshtasbi, who works as a dentist, said: "This method is not only painful for patients, but we also spread diseases and bacteria from unhealthy places in the mouth to healthy places. It is not only time-consuming but also dependent on the subjective judgment of the dentist, not So precise.” She also said that in order to avoid the patient's long-term discomfort, many times the dentist may “spot check” instead of accurately checking each tooth, which makes the disease likely to be missed.

The methods developed by Jokerst and colleagues can produce more comprehensive diagnostic results in a shorter period of time, and have quantifiable data that is not as dependent on the doctor's subjective judgment as traditional methods. According to Jokerst, ultrasound creates a spectrum of the sulcus around each tooth in the mouth and is much shorter than the manual time.

The study was tested in the pig's mouth and clinical research is being planned. There are both soft and hard tissues in the oral cavity, and ultrasonic testing has more application value and development space. Ultrasound can get a lot of oral data, how to make better use of this data to detect the health of various oral environments, and perhaps the need for artificial intelligence in the future.

Jokerst said that he still faces the challenge of how to improve the taste of squid ink, which is salty and bitter. But this does not seem difficult, he said: "We plan to add some mint to it."

Source: Health New Vision

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